Monday, 22 October 2012, 4:00 p.m., de Grand Pre Communication Centre, Seminar room, MNI
Dr. Jinny Kim, Director of the Centre for Functional Connectomics at the Korean Institute of Science and Technology
Dr. Kim has been responsible for the development of a number of very powerful genetic tools for the analysis of synaptic connectivity and neuronal excitability. Most recently she has published an important Nature Methods paper that adds vertebrate functionality to the GRASP (GFP Reconstitution Across Synaptic Partners) technology that had been developed and used originally by Cori Bargman’s lab in C. elegans for visualization of synapse formation in invertebrate models. For years this technology appeared not to work in the vertebrate CNS despite efforts by many teams to apply it. At Janelia Farm, she used clever computer-assisted protein design to develop mGRASP, a mammalian version of GRASP and to demonstrate its usefulness.